2. GPCR/G Protein Neuronal Signaling
  3. Neurotensin Receptor
  4. Latozinemab

Latozinemab  (Synonyms: AL001)

目录号: HY-P99688 纯度: 95.00%
COA

摩尔计算器

Latozinemab (AL001) 是一种重组人源抗 Sortilin 单克隆抗体。Latozinemab 以高亲和力有效结合 Sortilin，并阻断颗粒蛋白前体 (PGRN) 和 Sortilin 受体之间的相互作用。Latozinemab 具有引起额颞叶痴呆 (FTD) (FTD-GRN) 研究的颗粒蛋白原基因 (GRN) 突变的潜力。

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规格 价格 是否有货 数量
1 mg ￥3000
In-stock
5 mg ￥9000
In-stock
10 mg   询价  
50 mg   询价  

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Latozinemab 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Latozinemab (AL001) is a recombinant human anti-Sortilin monoclonal antibody. Latozinemab effectively binds Sortilin with a high affinity and blocks the interaction between progranulin protein (PGRN) and Sortilin receptor. Latozinemab has the potential for progranulin gene (GRN) mutations causative of Frontotemporal dementia (FTD) (FTD-GRN) research[1][2].

同型

Human IgG1 kappa
推荐同型对照抗体
种属

Human
Clinical Trial
性状

液体

颜色

Colorless to light yellow

运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG1 kappa
纯度 & 产品资料
参考文献

Latozinemab 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LatozinemabAL001AL 001AL-001Neurotensin ReceptorSortilinantibodyprogranulin proteinPGRNprogranulin geneGRNFrontotemporal dementiaFTDFTD-GRNInhibitorinhibitorinhibit

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